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Equinox is teaming up with lab-test startup Function Health to launch "Optimize by Equinox," a personalized health program that includes everything from personal training and nutrition plans to sleep coaching and massage therapy. "It's really a paradigm shift in how we're able to live with vitality and avoid suffering," said Jonathan Swerdlin, co-founder of Function Health. Function Health will test members for 100 biomarkers — everything from heart, liver and kidney health to metabolic and immune systems to cancer markers and nutrients. Equinox will then run its own battery of fitness tests, including VO2 max, strength and movement range. The fee doesn't include an Equinox gym membership, which brings the total to about $40,000 or more for the year.
Persons: Jonathan Swerdlin, Julia Klim, Equinox's, Klim, Swerdlin Organizations: Function, Pacific Locations: Philadelphia, Pacific Palisades, Los Angeles, New York City, Highland Park , Texas
“If we work with our physiology knowing that women are women and men are men, knowing that women are not small men, then imagine the (health) outcomes,” she said at a 2019 TED talk. Women of all ages should focus on strength training to help reduce risk of dementia, said exercise physiologist and nutrition scientist Dr. Stacy Sims (not shown). Dr. Stacy Sims said women should prioritize eating more protein to support building muscle, especially as bodies age. But if we have that lean mass from strength training, it really helps calm down that rate of change. Drinking something cold right after exercise helps bring that blood back centrally, reduces metabolites and starts the reparation process.
Persons: Joe Biden, , Stacy Sims, , MoMo, Sims, Darwin, that’s, Alzheimer’s, haven’t, It’s, , Melanie Radzicki McManus Organizations: CNN’s, CNN, TED, National Institutes of Health, Women’s, US National Institutes of Health Locations: Mount Maunganui , New Zealand
The Biden administration is designating two “forever chemicals,” man-made compounds that are linked to serious health risks, as hazardous substances under the Superfund law, shifting responsibility for their cleanup to polluters from taxpayers. The compounds, found in everything from dental floss to firefighting foams to children’s toys, are called forever chemicals because they degrade very slowly and can accumulate in the body and the environment. The chemicals are so ubiquitous that they can be detected in the blood of almost every person in the United States. One recent government study discovered PFAS chemicals in nearly half of the nation’s tap water. found the chemicals could cause harm at levels “much lower than previously understood” and that almost no level of exposure was safe.
Persons: Biden Organizations: Environmental Protection Agency Locations: United States
Colossal, 50-foot prehistoric snake discovered in India
  + stars: | 2024-04-18 | by ( Katie Hunt | ) edition.cnn.com   time to read: +4 min
CNN —A giant prehistoric snake longer than a school bus slithered around what is now India 47 million years ago, according to new research. A panoramic view of Panandhro Lignite Mine, in western India's Gujarat state, shows the fossiliferous level (red arrow) where the giant snake Vasuki indicus was found. However, the snake would have rivaled the largest known snake species — the extinct Titanoboa — in size. Snake size and the role of climateSnakes are cold-blooded and need heat from the environment to survive. Datta and Bajpai said the snake lived in a coastal marsh and swamp.
Persons: dwarfing, indicus, Shiva, Debajit Datta, Sunil Bajpai, , Datta, Verma Debajit, Bajpai, Titanoboa, Vasuki Organizations: CNN, Indian Institute of Technology Locations: India, Indian Institute of Technology Roorkee, Uttarakhand, India’s Gujarat, India's Gujarat, Colombia
CNN —Pregnancy complications, such as gestational diabetes or preeclampsia, may be linked to an elevated risk of death even decades after giving birth, according to a new study. The study, published Monday in the journal JAMA Internal Medicine, found that women who experienced major complications during pregnancy had an increased risk of early death and that risk remained elevated for more than 40 years. The data showed that more than 88,000 women had died and all five pregnancy complications were independently associated with a higher mortality risk later in life. Gestational diabetes was associated with a 52% increased risk of mortality, preterm delivery was associated with a 41% increased risk, delivering a baby with low birth weight was associated with a 30% increased risk, preeclampsia with a 13% increased risk and other hypertensive disorders with a 27% increased risk, the data showed. “We found that the increased mortality was attributable to multiple different causes of death, including heart disease, diabetes, respiratory disorders, and cancer,” he said.
Persons: Dr, Casey Crump, ” Crump, , , Ashley Roman, ” Roman, Crump, Joanne Stone, Raquel, Jaime Gilinski, ” Stone, Sanjay Gupta Organizations: CNN, The University of Texas Health Science Center, Lund University, NYU Langone Health, , of Obstetrics, Icahn School of Medicine, CNN Health Locations: UTHealth, Houston, Malmö, Sweden, United States, Mount
On Thursday, Seed Health launched CODA, a computational biology platform funded by its consumer business profitability. Seed Health has been in the business of microbiome scientific breakthroughs since its founding in 2015, but its biggest success to-date may have been becoming profitable as a bioscience startup. Katz's co-founder and co-CEO at Seed Health, Raja Dhir, said CODA and the accompanying data set will help to standardize microbiome science methods, which has long been an issue in the field. CODA's first applications are in metabolic health, brain health, longevity, and menopause, research areas chosen because they have already been identified as areas of human health where early CODA data displayed the strongest evidence. Seed Health has been working on several efforts around pioneering microbiome science for human and planetary health, and many in the field believe the approach is destined to have wider applications.
Persons: Katz, Ara Katz, Eran Segal, Eric Topol, transcriptome, Katz's, Raja Dhir, Dhir, Arpana Gupta, Goodman, There's, Segal, Joseph Petrosino, Petrosino Organizations: Seed, Seed Health, CNBC, Weizmann Institute of Science, Scripps Research Institute, UCLA, Luskin Microbiome, Baylor College of Medicine, Center, Metagenomics, Microbiome Research
For the first time, the Biden administration is requiring municipal water systems to remove six synthetic chemicals linked to cancer and other health problems that are present in the tap water of hundreds of millions of Americans. The extraordinary move from the Environmental Protection Agency mandates that water providers reduce perfluoroalkyl and polyfluoroalkyl substances, known collectively as PFAS, to near-zero levels. The compounds, found in everything from dental floss to firefighting foams to children’s toys, are called “forever chemicals” because they never fully degrade and can accumulate in the body and the environment. The chemicals are so ubiquitous that they can be found in the blood of almost every person in the United States. A 2023 government study of private wells and public water systems detected PFAS chemicals in nearly half the tap water in the country.
Persons: Biden Organizations: Environmental, Agency Locations: United States
Breakfast provides the brain with its first source of energy every morning. Fueling the brain is key for focus, clarity, and optimal functioning throughout the day. They also contribute to the neuroinflammation (inflammation around the brain) that's associated with brain fog and poor concentration. After that, here are five of my favorite breakfast brain foods. They're rich in key nutrients and functional compounds that promote better energy, clarity, and mental health.
Organizations: Psychiatry, Massachusetts General Hospital Locations: U.S, Massachusetts
He shared the five supplements he takes and those would never take with Business Insider. AdvertisementA top personal trainer who works with celebrities including Dakota Johnson shared the five supplements he takes every day with Business Insider. AdvertisementWorthington also avoids anything that claims to counteract blood sugar spikes. "Firstly, blood sugar spikes are a perfectly natural and essential part of metabolism," he said. "Wanting to eat food without elevating blood sugar is a little like hoping to exercise without elevating heart rate and blood pressure.
Persons: Luke Worthington, Worthington, , Dakota Johnson, Naomi Campbell, Jodie Comer, Luke Worthington Worthington, Rhiannon Lambert, I'm, isn't, Sophie Medlin, Katey Davidson Organizations: Business, Service, American Medical Association Locations: London, thermogenesis, cayenne
Some health experts have said that obesity drugs could shrink critical muscle mass, which could raise the risk of injuries and decrease strength. Those results are similar to those often seen with diet and exercise programs for weight loss. "There is a growing appreciation that the quality of weight loss is as important as the quantity of weight loss." For example, Eli Lilly is testing whether combining its weight loss drug with a monoclonal antibody from Versanis Bio might help patients lose weight while preserving muscle mass. The pharmaceutical giant recently acquired Versanis, which is part of a slate of companies targeting the muscle-loss aspect of weight loss.
Persons: Altimmune, Eli Lilly, Scott Harris Organizations: Novo Nordisk, Novo Nordisk's Ozempic Locations: Altimmune's, Novo
AdvertisementBloomer shared the four supplements that he takes his health from good to great. Fish oilBloomer takes a good quality fish oil every day for heart health and to prevent inflammation, he said. MultivitaminBloomer also takes a good quality multivitamin daily, while acknowledging the body of evidence that suggests they're useless. Protein powderTo ensure he's getting enough protein throughout the day, Bloomer two to three protein shakes a day. "It's relatively inexpensive, and you can get some really good quality proteins these days."
Persons: , Richard Bloomer, Bloomer, I've, Multivitamin Bloomer, they're Organizations: Service, Center, Nutraceutical, University of Memphis, Business, American Medical Association, Research Locations: Mount Sinai
CNN —It’s been nearly 13 years since “The Oprah Winfrey Show” came to an end, but for viewers of her weight loss special on Monday night, it likely felt like Winfrey’s talk show was back. “An Oprah Special: Shame, Blame and the Weight Loss Revolution” featured Winfrey doing what she proved for 25 seasons on “The Oprah Winfrey Show” she can do better than just about anyone else: bring people together and get them talking – and listening – to each other. Winfrey, too, shared the pain she has felt at times in her weight journey. “It’s not a matter of willpower.”The medical experts addressed potential side effects of weight loss medications and factors and risks that should be considered before taking it as part of a multiifaceted care plan. Winfrey spoke about her use of weight loss medication as one “tool” to manage her weight, combined with hiking, running, weight resistance training and eating a healthy diet.
Persons: CNN — It’s, Oprah Winfrey, , , Winfrey, ” Winfrey, Scott Butsch, Amanda Velazquez, It’s, ” Butsch, “ It’s, Let’s Organizations: CNN, Obesity, Metabolic, Cleveland Clinic Locations: United States, Sinai, Los Angeles
We delve into a wide range of topics, including the science behind new weight loss drugs, weight gain around menopause, and the evolutionary reasons behind why losing weight is so hard. Yeo truth No. 1: Losing weight ‘ain’t supposed to be easy’Losing weight goes against our self-preservation mechanisms. “I think we do have to fix our food environment; I think some people need to eat less food. But I think we need to love our food.”We hope these five tips help you think about food (and eating) in a more productive and less toxic way.
Persons: Sanjay Gupta, ” Giles Yeo, ” Yeo, Yeo, — Yeo, , , , Gene, it’s, “ Don’t, , Sanjay Gupta’s, Lindy West Organizations: CNN, American Medical Association, US Centers for Disease Control, University of Cambridge, Genetics, Obesity
The Food and Drug Administration on Thursday approved the first-ever treatment for a common and potentially deadly form of liver disease that affects millions worldwide. Novo Nordisk and Eli Lilly are testing their respective blockbuster weight loss injections as treatments for the same kind of liver disease, called nonalcoholic steatohepatitis, or NASH. Madrigal's drug, which will be marketed as Rezdiffra, is specifically approved to treat patients with NASH who also have moderate-to-advanced liver scarring. NASH is a serious form of liver disease characterized by excess fat buildup and inflammation in the liver and can lead to liver scarring, also known as fibrosis, along with liver failure and liver cancer. Roughly 6 million to 8 million people in the U.S. have NASH with moderate-to-advanced liver scarring, according to an estimate cited by the FDA.
Persons: Madrigal, Eli Lilly, NASH, Nikolay Nikolov, Rezdiffra Organizations: Madrigal Pharmaceuticals, Drug Administration, Pharmaceuticals, Novo Nordisk, FDA, Immunology Locations: U.S
5 tips to stop weight gain during menopause
  + stars: | 2024-03-10 | by ( Andrea Kane | ) edition.cnn.com   time to read: +7 min
(CNN) — Menopause and weight gain seem to go hand in hand. But is menopause really to blame for women’s midlife weight gain? Christmas said it’s impossible to talk about weight gain around menopause without talking about the other elephant in the room: aging. Many women gain weight around menopause. And there’s at least one more factor that contributes to weight gain as we age.
Persons: Sanjay Gupta ”, , I’ve, Monica Christmas, Christmas, Sanjay Gupta, , Julia Amaral, , ’ ”, it’s, Michael Pollan, don’t Organizations: CNN, University of Chicago Medicine, Locations: barre
Now, the company is betting on cancer drugs to help it regain its footing after a rocky year marked by the rapid decline of its Covid business. That $43 billion Seagen acquisition doubled Pfizer's oncology drug pipeline to 60 different experimental programs. Some analysts noted that it might take a few years for some of Pfizer's cancer drugs in mid-stage development to show pivotal clinical trial data and become less risky. Revenue from the blockbuster breast cancer drug Ibrance and prostate cancer treatment Xtandi, which Pfizer shares with Astellas Pharma, has declined over the past year. They are among the most expensive prescription drugs in the U.S. Before the Seagen deal, 94% of Pfizer's cancer products were small-molecule drugs.
Persons: Wall, Seagen, Chris Boshoff, Boshoff, David Ryder, Trung Huynh, Joe Biden's, Chris Schott, Suneet Varma, RemeGe, Merck, Padcev, Guggenheim, Pfizer's, Pfizer hasn't, Dr, Mikael Dolsten, Irfan Khan Organizations: Nurphoto, Getty, Pfizer, Astellas Pharma, Guggenheim, Bloomberg, UBS, Medicare, Drug Administration, FDA, ADC, JPMorgan, Drugs, CNBC, CVS Pharmacy, Los Angeles Times Locations: Covid, Bothell , Washington, U.S, biologics, China, Eagle Rock , California
SignosFounded in 2018, Signos uses continuous glucose monitors, or CGMs, and an artificial intelligence-powered app to help people better understand their metabolisms. But Signos' CGM system is meant for average consumers, so it is not intended for diabetes management. The Signos app walked me through the process step by step, offering a one-minute video and a series of GIFs I could watch. Another activity had me try and guess what I thought my glucose levels were at different points throughout the day. After eating a meal, I would often get a "Fast Rise" notification from my Signos app, which indicates that a glucose spike is occurring.
Persons: Ashley Capoot, I've, Signos, Dexcom, Sharam Fouladgar, you've, it's Organizations: CNBC, Abbott Laboratories, Centers for Disease Control, U.S . Food, Drug Administration, Dexcom Ventures, Bluetooth Locations: U.S, Mercer
Atrial fibrillation is dangerous and on the riseAtrial fibrillation is the leading cause of stroke in the United States. Atrial fibrillation can also lead to blood clots, heart failure and “can increase the risk for heart attack, for dementia, for kidney disease. Replacing both diet and added sugar sodas with water is best to reduce chances of atrial fibrillation, experts say. The rate of atrial fibrillation in the US population is growing: The CDC estimates some 12 million Americans will have A-fib by 2030. “Do not take it for granted that drinking low-sugar and low-calorie artificially sweetened beverages is healthy, it may pose potential health risks.”
Persons: , Penny Kris, Etherton, Kris, , Dr, Gregory Marcus, ” Marcus, Naveed Sattar, ” Sattar, Ningjian Wang, ” Wang Organizations: CNN, Pennsylvania State University, American Heart Association, US Centers for Disease Control, University of California, San Francisco School of Medicine, UCSF Health, Rhythm Society, University of Glasgow, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine Locations: United States, Scotland, Shanghai, China
Sleep is an important lifestyle factor in reducing risk for type 2 diabetes, a new study has found. In terms of risk for type 2 diabetes, there wasn’t a significant difference between those with normal sleep and those who slept six hours. And even for those who ate the healthiest, their diet didn’t offset the effects of insufficient sleep on diabetes risk. The findings are also based on participants’ recollections of their food and sleep habits, according to the study. Confirming a causal relationship “would require randomized trials intervening on sleeping habits to increase sleep time and see if this reduces risk of diabetes in those at risk, e.g.
Persons: CNN —, Dr, Diana Nôga, ” Nôga, , Leana Wen, Wen wasn’t, ” Wen, Naveed Sattar, ” Sattar, Wen Organizations: CNN, JAMA, biosciences, Uppsala University, Lighthouse Films, George Washington University Milken Institute School of Public Health, University of Glasgow Locations: Sweden, United Kingdom, Scotland,
Read previewUltra-processed foods have been linked with a higher risk of developing 32 health problems in a study. The studies looked at the amount of UPFs participants ate and if they developed any health problems. AdvertisementHowever, the researchers categorized the associations for most health problems as "low" or "very low" in credibility. It's unclear why UPFs are linked to so many health problemsThe review suggested several reasons why UPFs might be linked to health problems. Firstly, a person who eats a lot of UPFs may have a poor diet in general, which can lead to health problems.
Persons: , Evangeline Mantzioris, dietitians, dietitian Taylor Grasso, Gunter Kuhnle Organizations: Service, Business, University of South, University of Reading, International Agency for Research, Cancer Locations: University of South Australia
Just weeks after its initial public offering, Fractyl Health is catching Wall Street's attention as the next potential biopharmaceutical darling. Analysts are highlighting the company's groundbreaking therapies that directly target the gut and pancreas to ultimately induce Type 2 diabetes maintenance and weight loss. "Growing evidence indicates the gut is a core regulator of metabolism, placing gut dysfunction as a root cause of metabolic disease. Indeed, emerging consensus links modern diets to changes in the gut and pancreas that in turn increase an individual's risk of developing Type 2 Diabetes and obesity," Ulz wrote. gut) root cause of disease, could result in a more durable, disease-modifying treatment, differentiated from current, more burdensome (i.e.
Persons: Morgan Stanley, Jason Gerberry, Michael Ulz's, Ulz, Gerberry, Rejuva, America's Gerberry Organizations: Bank of America, Evercore ISI, Fractyl's, Bank, America's Locations: Fractyl
VKTX YTD mountain Viking shares year to date Then, Viking shares more than doubled in trading on Tuesday, putting the stock on pace to report a more than 300% year-to-date gain, after the company said its GLP-1/GIP receptor agonist VK2735 hit all its primary goals in a phase 2 clinical trial. The Tema Cardiovascular and Metabolic ETF (HRTS) , which is up 12% year to date, owns Novo, Lilly and Viking. Still early days Some analysts and investors admit it is still very early days for obesity treatment and many questions remain to be answered. "We continue to expect above consensus growth in the space, as we are bullish on adoption from payers and broader obesity uptake," Meacham wrote. For obesity only, Lilly has already gained a 38% share, despite only being in the market for 13 weeks, he said.
Persons: Eli Lilly, Geoff Meacham, Meacham, Lilly, Yuri Khodjamirian, Khodjamirian, Jeff Jonas, Becton Dickinson, Novo, BofA's Meacham, What's, Tema's, it's, Gabelli's Jonas, he's, William Blair, Andy Hsieh, Hsieh Organizations: Novo Nordisk, Bank of America, Centers for Disease Control, Zealand Pharma, Viking Therapeutics, Zealand, Food and Drug Administration, Novo, Metabolic, Therapeutics, Pharmaceuticals, Rock, AstraZeneca, Roche, Gabelli Funds, FDA, Viking, Merck, Pfizer Locations: U.S, Tema, Novo Nordisk's, GLP, Lilly
Citi reiterates Snowflake as a top pick Citi said Snowflake remains a top pick at the firm. Citi reiterates Micron as buy Citi said concerns about the stock underperformance is overdone and investors should buy the dip in top pick Micron. "We reiterate our Buy rating on Micron and maintain our price target of $95.00, above its historical average given the DRAM upturn and continued upside." "We are initiating coverage of Duolingo with a Buy rating and $222 price target (12x 2025 revenues)." Citi reiterates Nvidia as a top pick Citi said it's staying long shares of Nvidia.
Persons: Morgan Stanley, Rivian, Snowflake, Berenberg, Eli Lilly, Unilever, Edward Jones, Goldman Sachs, Piper Sandler, Piper, Datadog, Yuka Broderick, Janney, Argus, Wells, VZIO, MGY, Bernstein, it's, Evercore, Davidson Organizations: Citi, US pharma, Staples, Fractyl Health, Investor Relations, Strategic Finance, American Eagle Citi, Watch, Micron, UBS, Netflix, SUN, Kroger, Industry, Deutsche Bank, Deutsche, Seaport, Bank of America, Gas, Semiconductors, Nvidia, AMD, Seagate, Bank of, underperform Bank of America, JPMorgan, Comerica, CMA
Jim Cramer's daily rapid fire looks at stocks in the news outside the CNBC Investing Club portfolio. Walmart : The Arkansas-based retail giant's 3-for-1 stock split went into effect Monday, and Jim Cramer said he'd like to see other companies consider taking similar moves. "This is something that [CEO] Doug McMillon said that [founder] Sam Walton liked because people don't like partial stock. I think that companies like Broadcom should be listening to that, and they should be splitting," Cramer said. "They gave you a really long-term view, and it was very positive," Cramer said.
Persons: Jim Cramer's, Jim Cramer, Cramer, Doug McMillon, Sam Walton, Berkshire Hathaway, Warren Buffett's, there's, Buffett, it's, Boehringer Ingelheim, Eli Lilly, Organizations: CNBC, Club, Walmart, Broadcom, Cramer's Charitable Trust, Berkshire, Zealand Pharma Locations: Arkansas, Cramer's, Arbor , Michigan, Danish
5 tips for navigating childhood obesity
  + stars: | 2024-02-24 | by ( Andrea Kane | ) edition.cnn.com   time to read: +6 min
Editor’s note: Season 9 of the podcast “Chasing Life With Dr. Sanjay Gupta” explores the intersection between body weight and health. With children, doctors define obesity a bit differently than they do with adults. Severe obesity is having a BMI equal to or greater than the 120th percentile. “Most people who are heavy by the age of 5 or 6 will tend to continue to have problems with body weight throughout adolescence and into adulthood,” Yanovski said. “We know that those individuals will therefore accrue the greatest risks from their higher body (fat) because they’re going to continue to have high body weight throughout the years,” he said.
Persons: Sanjay Gupta ”, Dr, Jack Yanovski, Sanjay Gupta, ” Yanovski, , pediatricians, Organizations: CNN, National Institute of Child Health, Human Locations: Alabama
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